[Handle Methods] This protocol describes, in detail, how to synthesize RNA/DNA hybrid handles and how to anneal them to RNAs etc. The protocol also describes how to crosslink antibodies to polystyrene beads, should you want to make your own. Most people simply buy streptavidin or protein G functionalized beads from Spherotech or Bangs Labs, though.

[MedianCI.nb] Mathematica 8 function for calculating the confidence interval of the median. You provide a vector and the desired confidence interval, e.g. MedianCI[data, 0.05] to get the 95% CI. Mathematica's inbuilt MeanCI[data] provides the CI of the mean, but for data with outliers and/or lack of normality, the median is usually more suitable. This Mathematica function was directly translated from the one for R published at David-olives-median-confidence-interval.html.

[LogRank.nb] Mathematica 8 function for calculating the Log-Rank statistic for two Kaplan-Meier curves. Given event times and censoring information for two groups (e.g. treatment and control), gives the Chi-Squared, Log-Rank, Z, SE, and p-value. LogRank uses Mathematica 8's SurvivalDistribution[data] and related censoring and plotting functions. The code is based on Giuseppe Cardillo's excellent logrank code for MatLab (22317-logrank), but the p-value is not Yates' corrected.