Selected Publications


Molecular Architecture and Assembly Principles of Vibrio cholerae Biofilms
V. Berk, JCN. Fong, GT. Dempsey, ON. Develioglu, X. Zhuang, J. Liphardt, FH. Yildiz and S. Chu
Science 337, 236-239 (2012) [Full]
Science Editor's summary.

News and Views. Single molecules: Thermodynamic limits
J. Liphardt
Nature Physics 8, 638–639 (2012) [Full]

Scanning angle interference microscopy reveals cell dynamics at the nanoscale
MJ. Paszek, CC. DuFort, MG. Rubashkin, MW. Davidson, KS. Thorn, J. Liphardt and VM. Weaver
Nature Methods 9, 825-827 (2012) [Full]

Selectivity Mechanism of the Nuclear Pore Complex Characterized by Single Cargo Tracking
AR. Lowe, JJ. Siegel, P. Kalab, M. Sui, K. Weis and J. Liphardt
Nature 467, 600-603 (2010) [PDF]

Self-Organization of the Escherichia coli Chemotaxis Network Imaged with Super-Resolution Light Microscopy
D. Greenfield, AL. McEvoy, H. Shroff, GE. Crooks, NS. Wingreen, E. Betzig and J. Liphardt
PLoS Biology 7, e1000137 (2009) [PDF]
Science Editors' Choice commentary and Nature Chemical Biology Research Highlight.

Tunable nanowire nonlinear optical probe
Y. Nakayama, PJ. Pauzauskie, A. Radenovic, RM. Onorato, RJ. Saykally, J. Liphardt and P. Yang
Nature 447, 1098-1101 (2007) [PDF]
Cover article.

Use of Plasmon Coupling to Reveal the Dynamics of DNA Bending and Cleavage by Single EcoRV Restriction Enzymes
B. Reinhard, S. Sheikholeslami, A. Mastroianni, AP. Alivisatos and J. Liphardt
PNAS 104, 2667-2672 (2007) [PDF]

Light-powering Escherichia coli with proteorhodopsin
JM. Walter, D. Greenfield, CJ. Bustamante and J. Liphardt
PNAS 104, 2408-2412 (2007) [PDF]

Optical Trapping and Integration of Semiconductor Nanowire Assemblies in Water
PJ. Pauzauskie, A. Radenovic, E. Trepagnier, H. Shroff, P. Yang and J. Liphardt
Nature Materials 5, 97–101 (2006) [PDF]

A Molecular Ruler Based on Plasmon Coupling of Single Gold and Silver Nanoparticles
C. Sönnichsen, B. Reinhard, J. Liphardt and AP. Alivisatos
Nature Biotechnology 23, 741-745 (2005) [PDF]
Science News of the Week coverage.

Experimental Test of Hatano and Sasa's Nonequilibrium Steady-state Equality
EH. Trepagnier, C. Jarzynski, F. Ritort, GE. Crooks, CJ. Bustamante and J. Liphardt
PNAS 101, 15038-15041 (2004) [PDF]

Identifying Kinetic Barriers to Mechanical Unfolding of the T. thermophila Ribozyme
B. Onoa, S. Dumont, J. Liphardt, SB. Smith, I. Tinoco, Jr. and CJ. Bustamante
Science 299, 1892-1895 (2003) [PDF]

Equilibrium Information from Nonequilibrium Measurements in an Experimental Test of Jarzynski's Equality
J. Liphardt, S. Dumont, SB. Smith, I. Tinoco, Jr. and CJ. Bustamante
Science 296, 1832-1835 (2002) [PDF]

Reversible Unfolding of Single RNA Molecules Using Mechanical Force
J. Liphardt, B. Onoa, SB. Smith, I. Tinoco, Jr. and CJ. Bustamante
Science 292, 733-737 (2001) [PDF]
Science Perspectives commentary with some nice pictures by J. Fernandez, S. Chu and A. Oberhauser.

Reviews and Commentaries


What does physics have to do with cancer?
F. Michor, J. Liphardt, M. Ferrari and J. Widom
Nature Reviews Cancer 11, 657-670 (2011) [PDF]
Cover article.

Q & A: Single-molecule localization microscopy for biological imaging
AL. McEvoy, D. Greenfield, M. Bates and J. Liphardt
BMC Biology 8, (2010) [PDF]

Potential of light-harvesting proton pumps for bioenergy applications
JM Walter, D. Greenfield and J. Liphardt
Curr. Opin. Biotechnol. 21, (2010) [LINK]

The Great Hunt For Extra Compliance
J. Liphardt
Biophysical Journal 93, 4099 (2007) [PDF]

The Nonequilibrium Thermodynamics of Small Systems
F. Ritort, J. Liphardt and C. Bustamante
Physics Today, July (2005) [PDF]

Single Molecule Studies of DNA Mechanics
CJ. Bustamante, SB. Smith, J. Liphardt and D. Smith
Curr. Opin. Struct. Biol. 10, 279-285 (2000) [PDF]

Typos, Errors, and Notes


Science 292. Eq 3 is missing a minus sign - it should be e-(ko km/br)*e(bF-1). Also, the equation in the legend to figure 2 should be p(E)=1/(1 + eE/kT). The paper was originally quite long, and we moved a lot of stuff to a web supplement.

PNAS 104. Plasmon rulers paper. The units of the timescales in Figure 3, panels e-h, are wrong - they should be s and not ms. Panels a-d are correct.

PNAS 104. Proteorhodopsin paper. Supporting Information equation 9 is incorrect. The right side of the expression should be inverted.